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Update: Vaccine-preventable Infections and Immunization in Multiple Sclerosis

Practice Guideline, September 2019

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Some evidence suggests that infections may trigger MS relapses, increase MS radiologic and immunologic activity, and accelerate disease progression. Select reports link immunizations to clinical exacerbations of MS. Thus, it is understandable that patients with MS may have concerns about receiving recommended immunizations. The purpose of the current update is to systematically evaluate and incorporate new evidence, vaccines, and disease-modifying therapies (DMTs).

Reaffirmed on October 22, 2022.

Endorsed by the Consortium of Multiple Sclerosis Centers and by the Multiple Sclerosis Association of America.

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