2024 Annual Meeting | S1 - Alzheimer’s Disease and Related Dementias

Date Sunday 04/14/24

Time 01:00 PM - 03:00 PM MDT Add To Calendar

Location Colorado Convention Center | Four Seasons 1

Session Format This program will be presented both in-person and online

On Demand This program will be available in the meeting's On Demand product.

Event Type Scientific Platform Session

Moderator(s) Hyun-Sik Yang, MD, James R. Bateman III, MD

Topic(s) Aging, Dementia, and Behavioral Neurology

Learning Objectives A group of abstracts covering a similar topic will be presented in an oral format with presentations lasting eight minutes followed by four minutes of question and answer with the author.

CME Available 2.00 CME credits

Program Materials Program Evaluations

Event Timeline
01:00 PM - 01:24 PM MDT	Speaker	2024 Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases: This award recognizes major contributions to the understanding of the causes, prevention, treatment, and cure for Pick's, Alzheimer's, and related diseases. Francisco J. Lopera Restrepo, MD, PhD
01:24 PM - 01:36 PM MDT	Abstract	003 - Conversational Coherence in Alzheimer's Disease and Mild Cognitive Impairment: A Decision Tree Classifier Analysis Peter Pressman, MD
01:36 PM - 01:48 PM MDT	Abstract	004 - Clinical Relevance of Donanemab Treatment Alireza Atri, MD, PhD
01:48 PM - 02:00 PM MDT	Abstract	005 - Validation of Icobrain Aria - An AI-based Software Tool for Automated Detection and Quantification of Amyloid-related Imaging Abnormalities Annemie Ribbens
02:00 PM - 02:12 PM MDT	Abstract	006 - Preliminary Characterization of Language Network Connectivity in a Logopenic Alzheimer’s Population Using Task-based fMRI Lucas H. Oland
02:12 PM - 02:24 PM MDT	Abstract	007 - Breaking Diagnostic Barriers: NODDI-Machine learning Fusion for FTD Differential Diagnosis Edoardo G. Spinelli, MD
02:24 PM - 02:36 PM MDT	Abstract	008 - Machine Learning-enhanced Dementia Testing: Reliability and Accuracy of the Autonomous Cognitive Examination Calvin W. Howard, MD
02:36 PM - 02:48 PM MDT	Abstract	009 - Neuropathological Profile of Cases with Mild Cognitive Impairment Andrew Ho, DO
02:48 PM - 03:00 PM MDT	Abstract	010 - Diagnostic Performance and Clinical Applications of a Commercial Alpha-synuclein Seed Amplification Assay in a Tertiary Care Memory Clinic Amanda L. Porter, MD

Faculty Disclosures
Hyun-Sik Yang, MD	The institution of Dr. Yang has received research support from National Institutes of Health. Dr. Yang has received personal compensation in the range of $500-$4,999 for serving as a study section member with National Institutes of Health.
James R. Bateman III, MD	Dr. Bateman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novo Nordisk. The institution of Dr. Bateman has received research support from NIA. The institution of Dr. Bateman has received research support from Dementia Alliance of North Carolina. The institution of Dr. Bateman has received research support from Alzheimer's Association. The institution of Dr. Bateman has received research support from Alzheimer's Drug Discovery Foundation. Dr. Bateman has a non-compensated relationship as a Committee Member with UCNS that is relevant to AAN interests or activities.
Francisco J. Lopera Restrepo, MD, PhD	No disclosure on file
Carolyn Fredericks, MD	The institution of Dr. Fredericks has received research support from Alzheimer's Association. The institution of Dr. Fredericks has received research support from National Institute on Aging.
Lucas H. Oland	No disclosure on file
Joyce Li	No disclosure on file
Todd Constable	No disclosure on file
Cheryl Lacadie	No disclosure on file
Nadine Martin	No disclosure on file
Samantha Tun	Ms. Tun has nothing to disclose.
Anne Trainer	No disclosure on file
Suyeon Ju	No disclosure on file
Bronte Tani	No disclosure on file
Andrew Ho, DO	Dr. Ho has nothing to disclose.
Charles H. Adler, MD, PhD, FAAN	Dr. Adler has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Amneal. Dr. Adler has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Avion. Dr. Adler has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for CND Life Sci. Dr. Adler has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Jazz. Dr. Adler has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Precon. Dr. Adler has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Neurocrine. The institution of Dr. Adler has received research support from NIH. The institution of Dr. Adler has received research support from Michael J. Fox Foundation. The institution of Dr. Adler has received research support from Arizona Biomedical Research Commission. Dr. Adler has received publishing royalties from a publication relating to health care.
Parichita Choudhury, MD	The institution of Dr. Choudhury has received research support from Lewy Body Dementia Association. The institution of Dr. Choudhury has received research support from Arizona Alzheimer's Consortium.
David Shprecher, DO, FAAN	Dr. Shprecher has received personal compensation for serving as an employee of Banner Health. Dr. Shprecher has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Amneal. Dr. Shprecher has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Sanders+Parks. Dr. Shprecher has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Neurocrine. Dr. Shprecher has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Abbvie. Dr. Shprecher has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Kyowa Kirin. Dr. Shprecher has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Medplace. The institution of Dr. Shprecher has received research support from MJFF. The institution of Dr. Shprecher has received research support from Cognition Therapeutics. The institution of Dr. Shprecher has received research support from Biogen. The institution of Dr. Shprecher has received research support from Neuraly. The institution of Dr. Shprecher has received research support from Jazz Pharmaceuticals. The institution of Dr. Shprecher has received research support from Sanofi Aventis. The institution of Dr. Shprecher has received research support from Annovis. The institution of Dr. Shprecher has received research support from Neurocrine. The institution of Dr. Shprecher has received research support from Teva. The institution of Dr. Shprecher has received research support from Nuvelution. The institution of Dr. Shprecher has received research support from EIP Pharma. Dr. Shprecher has received personal compensation in the range of $500-$4,999 for serving as a Speaker with International Parkinson's and MDS. Dr. Shprecher has received personal compensation in the range of $5,000-$9,999 for serving as a Speaker with Parkinson's Movement Disorder Alliance.
Shyamal Mehta, MD, PhD, FAAN	Dr. Mehta has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Adamas Pharma. Dr. Mehta has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Abbott. Dr. Mehta has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for CNS Ratings.
Holly A. Shill, MD, FAAN	Dr. Shill has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sage Biogen. Dr. Shill has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Abbvie. Dr. Shill has received personal compensation in the range of $500-$4,999 for serving as a Consultant for KeifeRx. Dr. Shill has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Praxis Precision Medicine. Dr. Shill has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Fasikl Inc.
Erika Driver-Dunckley, MD, FAAN	Dr. Driver-Dunckley has nothing to disclose.
Christine Belden	No disclosure on file
Geidy Serrano	No disclosure on file
Thomas Beach	Thomas Beach has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Vivid Genomics. Thomas Beach has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Roche Diagnostics. The institution of Thomas Beach has received research support from National Institutes of Health. The institution of Thomas Beach has received research support from Michael J Fox Foundation . The institution of Thomas Beach has received research support from State of Arizona.
Alireza Atri, MD, PhD	Dr. Atri has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Prothena. Dr. Atri has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Eisai. Dr. Atri has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Novo Nordisk. Dr. Atri has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Lundbeck. Dr. Atri has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Merck. Dr. Atri has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novo Nordisk. Dr. Atri has received personal compensation in the range of $50,000-$99,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche/Genentech. Dr. Atri has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Lunbeck. The institution of Dr. Atri has received research support from National Institute of Aging (NIA). The institution of Dr. Atri has received research support from AZ Department of Health Services. The institution of Dr. Atri has received research support from Gates Ventures. The institution of Dr. Atri has received research support from Multiple companies, universities & consortia for contracted clinical trials to institution. The institution of Dr. Atri has received research support from Washington University in St. Louis. The institution of Dr. Atri has received research support from Foundation for NIH. The institution of Dr. Atri has received research support from ACTC/NIH. Dr. Atri has received publishing royalties from a publication relating to health care.
Cecilia Tremblay	No disclosure on file
Peter Pressman, MD	The institution of Dr. Pressman has received research support from the Doris Duke Fund to Retain Clinical Scientists . Dr. Pressman has received personal compensation in the range of $100,000-$499,999 for serving as a Associate Professor with University of Colorado School of Medicine.
Chelsea Chandler	No disclosure on file
Francesca Dino	No disclosure on file
Peter Foltz	No disclosure on file
Federica Agosta	Federica Agosta has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Philips. Federica Agosta has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier INC.
Silvia Basaia	Silvia Basaia has nothing to disclose.
Stefano Pisano, MD	Dr. Pisano has nothing to disclose.
Elisa Canu	The institution of Elisa Canu has received research support from Italian Ministry of Health .
Edoardo G. Spinelli, MD	Dr. Spinelli has nothing to disclose.
Giordano Cecchetti	Giordano Cecchetti has nothing to disclose.
Alma Ghirelli	Ms. Ghirelli has nothing to disclose.
Elisa Sibilla	No disclosure on file
Giuseppe Magnani	Giuseppe Magnani has nothing to disclose.
Francesca Caso, MD	Dr. Caso has nothing to disclose.
Paola Caroppo	No disclosure on file
Sara Prioni	No disclosure on file
Cristina Villa	No disclosure on file
Lucio Tremolizzo	No disclosure on file
Ildebrando H. Appollonio, MD	Dr. Appollonio has nothing to disclose.
Federico Verde	No disclosure on file
Nicola Ticozzi, MD	The institution of Dr. Ticozzi has received research support from Italian Ministry of Health . The institution of Dr. Ticozzi has received research support from AriSLA.
Vincenzo Silani, MD, FAAN	Dr. Silani has nothing to disclose.
Massimo Filippi, MD, FAAN	Dr. Filippi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Alexion, Almirall, Biogen, Merck, Novartis, Roche, Sanofi;. Dr. Filippi has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion, Biogen, Bristol-Myers Squibb, Merck, Novartis, Roche, Sanofi, Sanofi-Aventis, Sanofi- Genzyme, Takeda. Dr. Filippi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Bayer, Biogen, Celgene, Chiesi Italia SpA, Eli Lilly, Genzyme, Janssen, Merck-Serono, Neopharmed Gentili, Novartis, Novo Nordisk, Roche, Sanofi, Takeda, and TEVA. Dr. Filippi has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Springer Nature. The institution of Dr. Filippi has received research support from Biogen Idec, Merck-Serono, Novartis, Roche, the Italian Ministry of Health, the Italian Ministry of University and Research, and Fondazione Italiana Sclerosi Multipla.
Alette Wessels	No disclosure on file
Alexandra Atkins	No disclosure on file
Ming Lu	No disclosure on file
Julie Chandler	No disclosure on file
Wendy Ye	No disclosure on file
Ellen Dennehy	Ellen Dennehy has received personal compensation for serving as an employee of Eli Lilly. Ellen Dennehy has stock in Eli Lilly.
Dawn Brooks	No disclosure on file
John R. Sims, MD	Dr. Sims has received personal compensation for serving as an employee of Eli Lilly and Company. Dr. Sims has stock in Eli Lilly and Company.
Erin G. Doty, MD	Dr. Doty has received personal compensation for serving as an employee of Eli Lilly and Company, USA. Dr. Doty has received stock or an ownership interest from Eli Lilly and Company, USA.
Diana Sima	No disclosure on file
Dirk Smeets	No disclosure on file
Thanh Vân Phan	No disclosure on file
Simon Van Eyndhoven	No disclosure on file
Sophie Vercruyssen	No disclosure on file
Ricardo Magalhaes	No disclosure on file
Celine Maes	No disclosure on file
Joshua Guo	No disclosure on file
Richard W. Hughes, MBBS	Dr. Hughes has received personal compensation for serving as an employee of Biogen. Dr. Hughes has stock in Biogen.
Gioacchino Curiale, MD	Dr. Curiale has received personal compensation for serving as an employee of Biogen. Dr. Curiale has stock in Biogen.
Shibeshih Belachew, MD	Dr. Belachew has received personal compensation for serving as an employee of Biogen Inc. Dr. Belachew has received stock or an ownership interest from Biogen Inc.
Wim Van Hecke, PhD	Dr. Van Hecke has received personal compensation for serving as an employee of icometrix.
Annemie Ribbens	No disclosure on file
Paramita Saha-Chaudhuri	No disclosure on file
Refaat E. Gabr, PhD	Dr. Gabr has received personal compensation for serving as an employee of Biogen. Dr. Gabr has stock in Biogen.
Rafay Khan	No disclosure on file
Amanda L. Porter, MD	Dr. Porter has nothing to disclose.
Christian Lachner	No disclosure on file
Philip W. Tipton, MD	Dr. Tipton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for AbbVie. Dr. Tipton has received personal compensation in the range of $500-$4,999 for serving as a Speaker with Alzheimer's Tennessee. Dr. Tipton has received personal compensation in the range of $500-$4,999 for serving as a Speaker with Charlotte County Medical Society, Inc.
Neill R. Graff-Radford, MD, FAAN	The institution of Dr. Graff-Radford has received research support from Biogen. The institution of Dr. Graff-Radford has received research support from Lilly. The institution of Dr. Graff-Radford has received research support from Novartis. The institution of Dr. Graff-Radford has received research support from AbbVie. Dr. Graff-Radford has received publishing royalties from a publication relating to health care.
Gregory S. Day, MD, MSc, FAAN	Dr. Day has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Parabon Nanolabs. The institution of Dr. Day has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Eli Lilly. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Arialys Therapeutics. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Ionis. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for DynaMed (EBSCO Health). Dr. Day has stock in ANI Pharmaceuticals. The institution of Dr. Day has received research support from National Institutes of Health / NIA. The institution of Dr. Day has received research support from Chan Zuckerberg Initiative. The institution of Dr. Day has received research support from Alzheimer's Association. The institution of Dr. Day has received research support from National Institutes of Health / NINDS. The institution of Dr. Day has received research support from Horizon Therapeutics. The institution of Dr. Day has received research support from AVID Radiopharmaceuticals. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Presenter at Annual Meeting (CME) with American Academy of Neurology. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Content Development (CME) with PeerView, Inc. Dr. Day has received personal compensation in the range of $5,000-$9,999 for serving as a Content Development (CME) with Continuing Education, Inc. Dr. Day has a non-compensated relationship as a Clinical Director with AntiNMDA Receptor Encephalitis Foundation that is relevant to AAN interests or activities.
Calvin W. Howard, MD	Dr. Howard has received intellectual property interests from a discovery or technology relating to health care. Dr. Howard has a non-compensated relationship as a Founder with KiTH Solutions that is relevant to AAN interests or activities.
Marcus Ng, MD	The institution of Dr. Ng has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai Canada. The institution of Dr. Ng has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Paladin Canada. The institution of Dr. Ng has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Eisai Canada. The institution of Dr. Ng has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for UCB Canada. Dr. Ng has received publishing royalties from a publication relating to health care.