2024 Annual Meeting | S26 - Movement Disorders: Basic Science

Date Tuesday 04/16/24

Time 03:30 PM - 05:30 PM MDT Add To Calendar

Location Colorado Convention Center | Mile High 4EF

Session Format This program will be presented both in-person and online

On Demand This program will be available in the meeting's On Demand product.

Event Type Scientific Platform Session

Moderator(s) Ihtsham Haq, MD, FAAN, Claire Henchcliffe, MD, PhD, FAAN

Topic(s) Movement Disorders

Learning Objectives A group of abstracts covering a similar topic will be presented in an eight-minute oral format followed by four minutes for question and answer with the author.

CME Available 2.00 CME credits

Program Materials Program Evaluations

Event Timeline
03:30 PM - 03:54 PM MDT	Speaker	2024 Movement Disorders Research Award: This award recognizes an individual for outstanding work in the field of Parkinson's disease or other movement disorders for either a single outstanding contribution or for lifetime achievement. David Rubinsztein
03:54 PM - 04:06 PM MDT	Abstract	003 - Relationships Between Regional Burden of Tau Neuropathology and Age at Death and Disease Duration in Patients with Progressive Supranuclear Palsy Negin Badihian, MD
04:06 PM - 04:18 PM MDT	Abstract	004 - A Novel Diagnostic Method for Detection and Quantitation of Cutaneous Phosphorylated Alpha-synuclein Christopher H. Gibbons, MD, FAAN
04:18 PM - 04:30 PM MDT	Abstract	005 - a-Synuclein Aggregation Differentiates Parkinson’s Disease and Multiple System Atrophy in GI Tissue Tritia R. Yamasaki, MD, PhD, FAAN
04:30 PM - 04:42 PM MDT	Abstract	006 - Alpha-Synuclein Strains in Plasma Distinguish Parkinson's Disease from Dementia with Lewy Bodies George Kannarkat
04:42 PM - 04:54 PM MDT	Abstract	007 - Investigating the Indirect Interaction Between Vps35 and a-synuclein in Parkinson’s Disease Michele Persico, MD
04:54 PM - 05:06 PM MDT	Abstract	008 - Blood Mitochondrial DNA Copy Number Is Associated with Motor Symptoms and Dementia in Parkinson’s Disease Sun Ju Chung, MD, PhD, FAAN
05:06 PM - 05:18 PM MDT	Abstract	009 - Intraputaminal AAV-CAv1.3-shRNA Averts Levodopa-induced Dyskinesias and Ameliorates Long-standing Parkinsonian Motor Deficits in Aged Parkinsonian Macaques Margaret Caulfield, PhD
05:18 PM - 05:30 PM MDT	Abstract	010 - Striatal Cholinergic Agonist Infusion Induces a Dystonic Phenotype in Non-human Primate Edouard Courtin, MBBS

Faculty Disclosures
Ihtsham Haq, MD, FAAN	The institution of Dr. Haq has received research support from NINDS. The institution of Dr. Haq has received research support from the Parkinson's Foundation. The institution of Dr. Haq has received research support from NIMH. Dr. Haq has a non-compensated relationship as a consultant with Medtronics that is relevant to AAN interests or activities. Dr. Haq has a non-compensated relationship as a consultant with Boston Scientific that is relevant to AAN interests or activities. Dr. Haq has a non-compensated relationship as a consultant with Abbott that is relevant to AAN interests or activities.
Claire Henchcliffe, MD, PhD, FAAN	Dr. Henchcliffe has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Bayer. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving as a Consultant for AskBio. Dr. Henchcliffe has received personal compensation in the range of $0-$499 for serving as a Consultant for Certara. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Meira GTx. Dr. Henchcliffe has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for ProJenX. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Canary Global Inc . Dr. Henchcliffe has stock in Axent Biosciences Inc. The institution of Dr. Henchcliffe has received research support from Weston Brain Institute. The institution of Dr. Henchcliffe has received research support from Blue Rock Therapeutics. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving as a Speaker with Parkinson Study Group. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving as a Speaker with UCLA. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving as a Speaker travel with World Congress of Neurology. Dr. Henchcliffe has received personal compensation in the range of $0-$499 for serving as a Speaker travel with IAPRD. Dr. Henchcliffe has received personal compensation in the range of $0-$499 for serving as a Speaker travel with ASGCT. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving as a Speaker/Course director with AAN.
David Rubinsztein	No disclosure on file
	No disclosure on file
Michele Persico, MD	Dr. Persico has nothing to disclose.
Tracy-Shi Zhang Fang, PhD	Dr. Fang has nothing to disclose.
Simona Eleuteri	Simona Eleuteri has received intellectual property interests from a discovery or technology relating to health care.
David K. Simon, MD, PhD	Dr. Simon has received personal compensation in the range of $100,000-$499,999 for serving as a Consultant for Bial Biotech. An immediate family member of Dr. Simon has stock in Biogen. The institution of Dr. Simon has received research support from Weston Brain Institute. The institution of Dr. Simon has received research support from NIH. The institution of Dr. Simon has received research support from Neuraly. Dr. Simon has received personal compensation in the range of $5,000-$9,999 for serving as a Steering Committee Member: SPARK clinical study with Biogen. Dr. Simon has received personal compensation in the range of $500-$4,999 for serving as a Steering Committee Member: NILO-PD clinical study with Michael J Fox Foundation.
Carly Tucci	No disclosure on file
Man Mohan Mehndiratta, MD, MBBS, FAAN	Dr. Mehndiratta has nothing to disclose.
Margaret Caulfield, PhD	The institution of Dr. Caulfield has received research support from Department of Defense.
Kathy Steece-Collier, PhD	Prof. Steece-Collier has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for RegenxBio. Prof. Steece-Collier has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Pontifax. The institution of Prof. Steece-Collier has received research support from NIH/NINDS.
Molly Vander Werp	No disclosure on file
Scott Muller	No disclosure on file
Jennifer Stancati	No disclosure on file
Timothy Collier	No disclosure on file
Fredric Manfredsson	No disclosure on file
Yaping Chu	No disclosure on file
Ivette Sandoval	No disclosure on file
Jeffrey Kordower	No disclosure on file
Werner J. Becker, MD	Dr. Becker has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for AbbVie. Dr. Becker has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Lundbeck. Dr. Becker has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly. Dr. Becker has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Novartis. Dr. Becker has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Teva. Dr. Becker has received personal compensation in the range of $500-$4,999 for serving as a Consultant for McKesson. Dr. Becker has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for University of Calgary.
Sun Ju Chung, MD, PhD, FAAN	Dr. Chung has nothing to disclose.
Ji-Hye Oh	No disclosure on file
Sungyang Jo, MD	Dr. Jo has nothing to disclose.
Sangjin Lee	No disclosure on file
Jihyun Lee	No disclosure on file
Chang Ohk Sung	No disclosure on file
Christopher H. Gibbons, MD, FAAN	Dr. Gibbons has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Autonomic Neuroscience. Dr. Gibbons has stock in CND Life Sciences. Dr. Gibbons has received publishing royalties from a publication relating to health care. Dr. Gibbons has received personal compensation in the range of $5,000-$9,999 for serving as a Expert Advisor with Department of Justice.
Bailey Bellaire	No disclosure on file
Todd D. Levine, MD	Dr. Levine has received personal compensation for serving as an employee of CND life sciences . Dr. Levine has received personal compensation in the range of $100,000-$499,999 for serving as a Consultant for Nufactor. Dr. Levine has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Grifols. Dr. Levine has received personal compensation in the range of $50,000-$99,999 for serving as an Expert Witness for PNA. Dr. Levine has stock in CND Life Sciences. Dr. Levine has stock in Corinthian reference lab.
Roy L. Freeman, MD	Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Regenacy. Dr. Freeman has received personal compensation in the range of $100,000-$499,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Neurobo. Dr. Freeman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Vertex. Dr. Freeman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eli-Lilly. Dr. Freeman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Theravance. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Inhibikase. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier. Dr. Freeman has stock in Neurobo. Dr. Freeman has stock in Cutaneous NeuroDiagnostics. The institution of Dr. Freeman has received research support from NIH. The institution of Dr. Freeman has received research support from Theravance. The institution of Dr. Freeman has received research support from Biohaven. The institution of Dr. Freeman has received research support from Lundbeck.
Edouard Courtin, MBBS	Dr. Courtin has nothing to disclose.
Pierre Burbaud	No disclosure on file
Dominique Guehl	No disclosure on file
Bastien Ribot	No disclosure on file
Marc Deffains	No disclosure on file
Tritia R. Yamasaki, MD, PhD, FAAN	The institution of Dr. Yamasaki has received research support from Veteran's Affairs. The institution of an immediate family member of Dr. Yamasaki has received research support from Dept of Energy.
Lilia Turcios	No disclosure on file
Johannah Stegemann	No disclosure on file
Elena Ostrakhovitch	No disclosure on file
Saad Hulou	No disclosure on file
Negin Badihian, MD	Dr. Badihian has nothing to disclose.
Nirubol Tosakulwong	No disclosure on file
Stephen Weigand	No disclosure on file
Farwa Ali, MD	Dr. Ali has nothing to disclose.
Hugo Botha, MD	Dr. Botha has received research support from NIH.
Heather Clark	No disclosure on file
Julie Stierwalt	No disclosure on file
Rodolfo Savica, MD, PhD, FAAN	The institution of Dr. Savica has received research support from ACADIA Pharmaceuticals, Inc.
Dennis W. Dickson, MD	Dr. Dickson has nothing to disclose.
Jennifer Whitwell, PhD	Dr. Whitwell has nothing to disclose.
Keith A. Josephs, Jr., MD, FAAN	Dr. Josephs has nothing to disclose.
George Kannarkat	Dr. Kannarkat has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Guidepoint Global.
Alice Chen-Plotkin, MD	Dr. Chen-Plotkin has received intellectual property interests from a discovery or technology relating to health care.
Rebecca Zack	No disclosure on file
Robert Skrinak	No disclosure on file
James F. Morley, MD, PhD	Dr. Morley has nothing to disclose.
Roseanne Davila-Rivera	No disclosure on file
Sanaz Arezoumandan, MD	Ms. Arezoumandan has nothing to disclose.
Katherine Dorfman	Ms. Dorfman has nothing to disclose.
Kelvin Luk	No disclosure on file
Daniel Weintraub	Daniel Weintraub has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Clintrex. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Janssen. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sage. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Scion. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Signant. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sunovion. Daniel Weintraub has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Modality.ai. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Cerevel. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for CuraSen. Daniel Weintraub has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Takeda. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Boehringer Ingelheim. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Daniel Weintraub has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Acadia. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Movement Disorder Society. The institution of Daniel Weintraub has received research support from NIH. The institution of Daniel Weintraub has received research support from Fox Foundation. The institution of Daniel Weintraub has received research support from IPMDS. Daniel Weintraub has received intellectual property interests from a discovery or technology relating to health care.
Thomas F. Tropea, DO	Dr. Tropea has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Bial. The institution of Dr. Tropea has received research support from NINDS. The institution of Dr. Tropea has received research support from Parkinson Foundation. The institution of Dr. Tropea has received research support from Michael J Fox Foundation.
Edward Lee	No disclosure on file
Virginia Lee, PhD	Virginia Lee, PhD has nothing to disclose.
David Irwin, MD	The institution of Dr. Irwin has received research support from NIH. The institution of Dr. Irwin has received research support from Prevail. The institution of Dr. Irwin has received research support from Passage Bio. The institution of Dr. Irwin has received research support from Alector. The institution of Dr. Irwin has received research support from Transposon. The institution of Dr. Irwin has received research support from Denali.
Rizwan Akhtar, MD	The institution of Dr. Akhtar has received research support from Vanqua Bio. The institution of Dr. Akhtar has received research support from Fox Foundation for Parkinson Research.