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Immunosuppressive treatment for GBs

Measure Purpose: Decrease the duration of functional impairment in Guillain-Barre Syndrome (GBS)

The numerator: Patients admitted to an inpatient facility with GBS who are nonambulatory with documentation that immunosuppressive therapy using plasmapheresis (PE) or intravenous immunoglobulin (IVIG) given and not prescribed corticosteroids

is divided by

The denominator: Patients admitted to inpatient facility with confirmed diagnosis of GBS who are nonambulatory

Exclusions are removed from the denominator for: 

  • Alternative diagnosis suspected and treated
  • GBS refractory to first line treatments
  • Patient has a previous history of severe systemic or anaphylactic response to IVIG
  • Patient is known to have anti-IgA antibodies with selective IgA deficiencies
  • Patient cannot tolerate central line placement
  • Patient is actively septic or hemodynamically unstable
  • Patient has an allergy to fresh frozen plasma or albumin
  • Patient has a heparin allergy that prevents receiving heparin as an anticoagulant during plasmapheresis
  • Patient with hypocalcemia
  • Patients that are beyond four weeks of onset
  • Patients who refuse

Key Phrases

Key phrases you should use to meet this measure include:

  • Patient prescribed immunosuppressive therapy
  • Patient prescribed plasmapheresis
  • Patient prescribed PE
  • Patient prescribed IVIG
  • Patient prescribed intravenous immunoglobulin

Measure Calculation Example

Dr. Sousa has 13 patients on his hospital service with a confirmed diagnosis of Guillain-Barre Syndrome. This is the denominator. One patient cannot tolerate central line placement and one is beyond 4 weeks of onset. These two patients are removed from the denominator.

Of the remaining 11 patients, six of them received PE and one received IVIG. This is the numerator.

Quality of patient care = 7/(13-2). Dr. Sousa has a score of 63% for this measure.