Abstract Details Title Factors associated with insomnia in the Peruvian population during social isolation due to the COVID-19 pandemic Topic Sleep Presentation(s) Sleep Posters (7:00 AM-5:00 PM) Poster/Presentation Number 003 Background Social isolation measures, such as quarantines, limit the spread of infectious diseases with high pandemic potential. Today, because of the health emergency caused by the outbreak of the SARS-CoV-2 virus, many countries in various parts of the world have decreed a series of measures to safeguard the health of their citizens, restricting their mobility, social interactions, and daily activities. However, these actions cause economic, social, and mental health problems in those affected, the latter being the most prominent. They are the cause of the previous two, one of the most common forms of expressing this type of problem being sleep disorders. Objective The objective of this study, is to determine the factors associated with insomnia in the Peruvian population during the COVID-19 quarantine. Design/Methods We carried out a cross-sectional, observational, and prospective study. The study included the resident population of Peru between 18 and 60 years subjected to quarantine during June 2020. An online questionnaire was applied (using Google Forms®), consisting of the Insomnia Severity Index, the Hospital Anxiety and Depression Scale, and the Pittsburg Sleep Quality Index. Multivariate regression analyses were performed to identify factors associated with insomnia. Results A total of 383 participants, aged 21.5 years, were included in the analysis; 56.7% were male. Fifty-two percent resided in the northern region of Peru, and 28.6% reported having had COVID-19. The proportion of insomnia in the sample was 75.2%; 56.7% had anxiety, 49.3% depression, and 88.7% low sleep quality. Finally, presenting anxiety was associated with RP=1.55 (IC95%=1.09-2.2). Conclusions We found a high proportion of insomnia and other mental disorders in the study and an association between insomnia and anxiety in Peruvian residents quarantined for COVID-19. Authors/Disclosures PRESENTER No disclosure on file No disclosure on file No disclosure on file