Of the 40 patients examined, 20 began experiencing dizziness after testing positive for COVID-19 and 20 reported dizziness after receiving the vaccines. All patients had brain MRI, but no MRI findings indicated inflammatory changes from infections or antibody reactions. Only five of 40 patients had abnormal VNG indications of uncompensated peripheral vestibulopathy which could be related to virus infections or antibody reactions. Thirty out of 40 patients had histories of anxiety, depression, other mood disorders, or family histories of mood disorders. Based on the clinical history and examinations, along with MRI findings and comprehensive vestibular testing, 75% of the 40 patients had diagnoses of persistent perceptual positional vertigo (PPPV), which was most likely related to patients’ underlying anxiety, depression, or mood disorders.