Abstract Details

Title Longitudinal Myelitis as a COVID-19 Neurological Manifestation

Topic Multiple Sclerosis

Presentation(s) P11 - Poster Session 11 (11:45 AM-12:45 PM)

Poster/Presentation
Number 12-004

Background

While there is an established link between viral infections and new-onset demyelinating diseases [1, 2], data on the association between SARS-CoV-2 and myelitidies is lacking.

Objective

To present a case of a longitudinal myelitis (LM) in the setting of SARS-CoV-2 infection.

Design/Methods Consent obtained from patient.

Results

A 53-year-old man presented with epigastric pain and urinary retention following ten days of fever, chills, headache, and cough. On presentation, he tested positive for SARS-CoV-2, prompting admission, then subsequently developed bilateral lower extremity weakness and numbness. MRI revealed T2 cord hyperintensity from C7 caudally to the conus. CSF revealed elevated total protein (67), WBC (16), IgG (11.1), and myelin-based protein (9). Testing for other demyelinating, infectious, and inflammatory conditions was negative. He had modest improvement in sensation following intravenous methylprednisolone and plasma exchange although remains paraplegic.

Conclusions

This unique case of a longitudinal myelitis in the setting of SARS-CoV-2 infection adds to previously reported cases of acute disseminated encephalomyelitis, meningoencephalitis, and optic neuritis as neurological manifestations of SARS-CoV-2 infections [2].

Authors/Disclosures
Lindsay Celentano PRESENTER	Mrs. Celentano has nothing to disclose.
Alexander Besser, DO	Dr. Besser has nothing to disclose.
Amaris Alayon, MD (University of Miami/Jackson Health System)	Ms. Alayon has nothing to disclose.
Adnan Subei, DO, FAAN (Neurology Consultants of Dallas)	Dr. Subei has received personal compensation for serving as an employee of Neurology Consultants of Dallas. Dr. Subei has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Efficient. Dr. Subei has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Biogen. Dr. Subei has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Bristol Meyer Squibb. Dr. Subei has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for TG Therapeutics. Dr. Subei has received personal compensation in the range of $50,000-$99,999 for serving on a Speakers Bureau for EMD Serono. Dr. Subei has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Alexion. Dr. Subei has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Amgen.