In this case series, we present six cases of GBS in the setting of SARS-CoV-2 infection seen at our institution.
CASE DESCRIPTION:
Case 1/2: 88 and 80 year old females who both presented with ascending weakness and sensory deficits and had diminished reflexes on examination. Both tested positive for SARS-CoV-2 infection prior to symptom onset. CSF and electrodiagnostic work up were only performed for the second case, which demonstrated albuminocytologic dissociation and severe acute polyradiculitis, respectively.
Case 3: 57 year old male who presented with left facial weakness and asymmetric hemibody weakness with diffusely reduced reflexes. He tested positive for COVID-19 infection after symptom onset. CSF studies demonstrated albuminocytologic dissociation.
Case 4/5: 45 and 37 year old females who both presented with bilateral facial and lower extremity weakness and reduced reflexes. Following SARS-CoV-2 infection, CSF evaluation in both cases revealed albuminocytologic dissociation. Electrodiagnostic evaluation in the second case demonstrated acute demyelinating polyradiculopathy.
Case 6: 60 year old female who presented with right eye ptosis and right lower extremity weakness/numbness following upper respiratory symptoms. Tested positive for SARS-CoV-2 infection. CSF evaluation demonstrated albuminocytologic dissociation.