50 patients underwent RAVLT and 48 underwent LMT. Epilepsy duration, seizure frequency, and antiseizure medication load did not differ between normal and impaired VM groups. TBSS revealed significant differences in WM integrity between patients with poor and normal performance in the LMT and RAVLT tests. Compared to patients with normal VM, patients with poor performance in the LMT, displayed decreased FA in the left corticospinal tract, superior longitudinal fasciculus, corpus callosum, forceps major, anterior thalamic radiation, inferior fronto-occipital fasciculus, inferior longitudinal fasciculus and uncinate fasciculus. Patients who performed worse in the RAVLT had more diffuse WM damage compared to patients with preserved RAVLT VM performance. In comparison with controls, both patient groups, regardless of performance, showed diffusely decreased FA.