2022 Annual Meeting | S36 - Movement Disorders: Clinical and Pathologic Characterization of Neurodegenerative Movement Disorders

Date Thursday 04/07/22

Time 01:00 PM - 03:00 PM PDT Add To Calendar

Session Format This program will be presented both in-person and online

On Demand This program will be available in the meeting's On Demand product.

Event Type Scientific Platform Session

Moderator(s) Nikolaus McFarland, MD, PhD, FAAN, Sheng-Han Kuo, MD

Topic(s) Movement Disorders

CME Available 2.00 CME credits

Program Materials Program Evaluations

Event Timeline
01:00 PM - 01:00 PM PDT	Speaker	Walk-in Slides Erin Jackson
01:00 PM - 01:12 PM PDT	Abstract	001 - Clinical spectrum of corticobasal degeneration: review of 238 autopsy-confirmed patients Shunsuke Koga, MD, PhD
01:12 PM - 01:24 PM PDT	Abstract	002 - Later Onset Multiple System Atrophy: Poor Prognosis and Diagnostic Challenge Hiroaki Sekiya, MD, PhD
01:24 PM - 01:36 PM PDT	Abstract	003 - Tau histopathological lesion type correlates of structural magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) biomarkers in 4-repeat tauopathies.
01:36 PM - 01:48 PM PDT	Abstract	004 - Inhibition of C1q Reduces Nerve Damage as Measured by Neurofilament Light Chain in the HD R6/2 Mouse Model Yaisa Andrews-zwilling
01:48 PM - 02:00 PM PDT	Abstract	005 - Cutaneous Alpha-Synuclein Detection in Patients with Suspected Synucleinopathies Christopher H. Gibbons, MD, FAAN
02:00 PM - 02:12 PM PDT	Abstract	006 - Glucocerebrosidase Deficiency Mediates Propagation of Protein Aggregation in Neurodegeneration via Modification of Extracellular Vesicles Marie Y. Davis, MD, PhD
02:12 PM - 02:24 PM PDT	Abstract	007 - Preclinical In Vivo Characterization of UCB0599, an Orally Available, Small Molecule Inhibitor of a-Synuclein Misfolding in Development for Parkinson’s Disease Diana L. Price, PhD
02:24 PM - 02:36 PM PDT	Abstract	008 - Patterns of TDP-43 Deposition in Brains with LRRK2 G2019S Mutations Julian Agin-Liebes, MD
02:36 PM - 02:48 PM PDT	Abstract	009 - Longitudinal Treatment Patterns for Chorea in Patients with Huntington Disease: Data from Enroll-HD Erin Furr-Stimming, MD, FAAN
02:48 PM - 03:00 PM PDT	Abstract	010 - Mitochondrial Antigen Presentation In Correlation To Parkinson's Disease-like Symptoms. Moustafa N. Badr, PhD

Faculty Disclosures
	No disclosure on file
Marie Y. Davis, MD, PhD	Dr. Davis has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. The institution of Dr. Davis has received research support from NIH NINDS. The institution of Dr. Davis has received research support from University of Washington Institute for Stem Cell and Regenerative Medicine. The institution of Dr. Davis has received research support from VA BLRD. Dr. Davis has received personal compensation in the range of $500-$4,999 for serving as a study section grant reviewer with NIH. Dr. Davis has received personal compensation in the range of $500-$4,999 for serving as a Grant reviewer with Parkinson's Foundation.
Naomi Kouri	No disclosure on file
Christopher H. Gibbons, MD, FAAN	Dr. Gibbons has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Autonomic Neuroscience. Dr. Gibbons has stock in CND Life Sciences. Dr. Gibbons has received publishing royalties from a publication relating to health care. Dr. Gibbons has received personal compensation in the range of $5,000-$9,999 for serving as a Expert Advisor with Department of Justice.
Marina Buciuc, MD	Dr. Buciuc has nothing to disclose.
Keith A. Josephs, Jr., MD, FAAN	Dr. Josephs has nothing to disclose.
Dietrich Haubenberger, MD, FAAN	Dr. Haubenberger has received personal compensation for serving as an employee of Neurocrine Biosciences, Inc. Dr. Haubenberger has stock in Neurocrine Biosciences. Dr. Haubenberger has a non-compensated relationship as a Member of the Board with American Society for Experimental Neurotherapeutics that is relevant to AAN interests or activities.
Hugo Botha, MD	Dr. Botha has received research support from NIH.
Moustafa N. Badr, PhD	Mr. Badr has nothing to disclose.
Mary M. Machulda, PhD	The institution of Dr. Machulda has received research support from NIH.
Roy Alcalay, MD	Dr. Alcalay has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Genzyme/Sanofi. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Gain Therapeutics. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Vanqua Bio. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Takeda. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biohaven. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Capsida. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Servier. The institution of Dr. Alcalay has received research support from Michael J. Fox Foundation. The institution of Dr. Alcalay has received research support from Parkinson's Foundation. The institution of Dr. Alcalay has received research support from Silverstein Foundation. Dr. Alcalay has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant with Parkinson's Foundation.
Ted Yednock, PhD	Ted Yednock, PhD has received personal compensation for serving as an employee of Annexon Inc. Ted Yednock, PhD has received personal compensation in the range of $100,000-$499,999 for serving as an officer or member of the Board of Directors for Annexon Inc. Ted Yednock, PhD has received stock or an ownership interest from Annexon Inc. Ted Yednock, PhD has received intellectual property interests from a discovery or technology relating to health care.
Stephen Weigand	No disclosure on file
Yaisa Andrews-zwilling	No disclosure on file
Richard Hickman	No disclosure on file
Matthew Senjem	Matthew Senjem has received stock or an ownership interest from Align Technology, Inc.. Matthew Senjem has received stock or an ownership interest from Inovio Biomedical Corp.. Matthew Senjem has received stock or an ownership interest from Johnson & Johnson. Matthew Senjem has received stock or an ownership interest from Mesa Laboratories, Inc.. Matthew Senjem has received stock or an ownership interest from Nvidia Inc.. Matthew Senjem has received stock or an ownership interest from LHC Group, Inc.. Matthew Senjem has received stock or an ownership interest from Natus Medical Incorporated. Matthew Senjem has received stock or an ownership interest from Varex Imaging Corporation. Matthew Senjem has received personal compensation in the range of $100,000-$499,999 for serving as a IT Technical Specialist II with Mayo Clinic.
Rene Utianski	No disclosure on file
Christopher Schwarz	No disclosure on file
Heather Clark	No disclosure on file
Riki Matsumoto, MD	Dr. Matsumoto has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for Eisai. Dr. Matsumoto has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for UCB Japan. Dr. Matsumoto has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for Daiichi-Sankyo. Dr. Matsumoto has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for Ostuka.
Selina Yu	No disclosure on file
Joseph Duffy	No disclosure on file
Arnav Khera	Mr. Khera has nothing to disclose.
Clifford R. Jack, Jr., MD	The institution of Dr. Jack has received research support from NIH. The institution of Dr. Jack has received research support from Alexander Family Alzheimer's Disease Research Professorship of the Mayo Clinic.
Roy L. Freeman, MD	Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Regenacy. Dr. Freeman has received personal compensation in the range of $100,000-$499,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Neurobo. Dr. Freeman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Vertex. Dr. Freeman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eli-Lilly. Dr. Freeman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Theravance. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Inhibikase. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier. Dr. Freeman has stock in Neurobo. Dr. Freeman has stock in Cutaneous NeuroDiagnostics. The institution of Dr. Freeman has received research support from NIH. The institution of Dr. Freeman has received research support from Theravance. The institution of Dr. Freeman has received research support from Biohaven. The institution of Dr. Freeman has received research support from Lundbeck.
Aya Murakami, MD, PhD	Dr. Murakami has nothing to disclose.
Daniel O. Claassen, MD, FAAN	Dr. Claassen has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Teva Neuroscience. Dr. Claassen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Spark . The institution of Dr. Claassen has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Alterity. Dr. Claassen has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Teva Neuroscience. Dr. Claassen has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for HD Insights. The institution of Dr. Claassen has received research support from NIH. The institution of Dr. Claassen has received research support from CHDI. The institution of Dr. Claassen has received research support from HDSA. The institution of Dr. Claassen has received research support from Department of Defense. The institution of Dr. Claassen has received research support from Griffin Family Foundation. The institution of Dr. Claassen has received research support from Neurocrine. The institution of Dr. Claassen has received research support from Vaccinex. The institution of Dr. Claassen has received research support from AbbVie. The institution of Dr. Claassen has received research support from CHDI. The institution of Dr. Claassen has received research support from Genentech/ Roche. The institution of Dr. Claassen has received research support from Prilenia. The institution of Dr. Claassen has received research support from Neurocrine/ HSG.
Erin Furr-Stimming, MD, FAAN	Dr. Furr-Stimming has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Teva Pharmaceuticals. Dr. Furr-Stimming has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Michael J. Fox Foundation. Dr. Furr-Stimming has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Medscape. Dr. Furr-Stimming has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Teva Pharmaceuticals. The institution of Dr. Furr-Stimming has received research support from Huntington's Disease Society of America. The institution of Dr. Furr-Stimming has received research support from Roche/Genetech. The institution of Dr. Furr-Stimming has received research support from Uniqure. The institution of Dr. Furr-Stimming has received research support from CHDI. The institution of Dr. Furr-Stimming has received research support from Huntington Study Group/Neurocrine. The institution of Dr. Furr-Stimming has received research support from NIH/University of Iowa. The institution of Dr. Furr-Stimming has received research support from Sage Therapeutics. Dr. Furr-Stimming has received publishing royalties from a publication relating to health care.
Nirubol Tosakulwong	No disclosure on file
Hiroaki Sekiya, MD, PhD	Dr. Sekiya has nothing to disclose.
Dennis W. Dickson, MD	Dr. Dickson has nothing to disclose.
Karen S. Marder, MD, MPH, FAAN	Dr. Marder has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech. Dr. Marder has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Parkinson's Foundation . Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for CHDI. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for PTC therapeutics. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Springer LTD. The institution of Dr. Marder has received research support from Vaccinex. The institution of Dr. Marder has received research support from Genentech. The institution of Dr. Marder has received research support from Triplet Therapeutics. The institution of Dr. Marder has received research support from Prilenia.
Raja E. Estes, BS	Ms. Estes has nothing to disclose.
Richard P. Mayeux, MD, MSc, FAAN	Dr. Mayeux has nothing to disclose.
Jennifer Whitwell, PhD	Dr. Whitwell has nothing to disclose.
Todd D. Levine, MD	Dr. Levine has received personal compensation for serving as an employee of CND life sciences . Dr. Levine has received personal compensation in the range of $100,000-$499,999 for serving as a Consultant for Nufactor. Dr. Levine has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Grifols. Dr. Levine has received personal compensation in the range of $50,000-$99,999 for serving as an Expert Witness for PNA. Dr. Levine has stock in CND Life Sciences. Dr. Levine has stock in Corinthian reference lab.
Shunsuke Koga, MD, PhD	Dr. Koga has nothing to disclose.
J. E. Ahlskog, MD, PhD	Dr. Ahlskog has received publishing royalties from a publication relating to health care.
Farwa Ali, MD	Dr. Ali has nothing to disclose.
Diana L. Price, PhD	Dr. Price has received personal compensation for serving as an employee of Neuropore Therapies, Inc.. Dr. Price has stock in ACADIA Pharmaceuticals.
Irene Litvan, MD, FAAN	Dr. Litvan has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Lundbeck. Dr. Litvan has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Frontiers in Neurology.
Alessia Tassoni	No disclosure on file
Jessica Young	No disclosure on file
Robert I. Reid	No disclosure on file
Ece Bayram, MD, PhD	The institution of Dr. Bayram has received research support from National Institute on Aging (K99AG073453). The institution of Dr. Bayram has received research support from Lewy Body Dementia Association. The institution of Dr. Bayram has received research support from National Institute of Neurological Disorders and Stroke.
Leo Pallanck	No disclosure on file
Julian Agin-Liebes, MD	Dr. Agin-Liebes has nothing to disclose.
Kenji Sekiguchi, MD, PhD	Dr. Sekiguchi has nothing to disclose.
Nikolaus McFarland, MD, PhD, FAAN	Dr. McFarland has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sutter Health. The institution of Dr. McFarland has received research support from NIH. Dr. McFarland has received publishing royalties from a publication relating to health care.
Sheng-Han Kuo, MD	Dr. Kuo has nothing to disclose.
Erin Jackson	Ms. Jackson has nothing to disclose.