2023 Annual Meeting | De Novo SPG4 Consortium (Non-AAN Sponsored Event) Date Tuesday 04/25/23 Time 05:30 PM - 07:00 PM EST Add To Calendar Event Type ICW Description De Novo SPG4 is a rare disease due to SPAST gene mutations which when occurring de novolead to a phenotype of childhood onset cerebral palsy rather than inherited mutations in thisgene which lead to adult onset spastic paraparesis.